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The “Get Pregnant in No Time” Formula

Written by:, PhD, Founder and Inventor of the Proov test — the first and only FDA-cleared test to confirm successful ovulation at home.

By Dr. Cleopatra

The Fertility Strategist

Executive Director, The Fertility & Pregnancy Institute

Founder of the Primemester™ Protocol and the Get Pregnant in No Time Formula


Whether you’re just starting to think about having babies, or you’re starting to lose hope because you’ve been trying for months or years, I want you to know that you are seen, loved, and supported. There are scientists hard at work to uncover and solve the root causes of fertility challenges. I am one of those scientists, and I want to teach you about the exciting and potent science of primemester epigenetics. 

You might be wondering what the primemester is. You might even be wondering what I mean by epigenetics. Let me break these down before we dive in!

The primemester is the period leading up to pregnancy, and it is truly one of the most important windows of opportunity that we will ever have. It is during this window of opportunity that we can literally change the quality and expression of the genes that we pass down to our babies (and grandbabies!). 

Which brings me to epigenetics. Epi means “above” in Greek, so the literal translation of the word epigenetics is “above genetics.” Epigenetics means that your DNA is not your destiny—especially if how you care for yourself takes into account your unique DNA. Through epigenetics, you have the power to shape how your genes express themselves to produce your mental and physical health, including your fertility. Science shows that you can suppress or activate the expression of your genes through what you think, what you consume, how you move your body, and how you connect with other humans and nature.

This area of scientific inquiry and clinical practice is the key to getting pregnant quickly and easily, staying pregnant, and finally having the superbaby you’ve been dreaming of for as long as you can remember.

The real-world application of the science of primemester epigenetics is known as the Primemester Protocol. The Primemester Protocol is the result of decades of meticulous science, experimentation, and refinement. To date, it has helped mamas in their 20s, 30s, and 40s in 18 countries on 6 continents have their babies. 

Personal Note 

I may be the brain behind the Primemester Protocol, but my most important and cherished roles in the world are Mama and Wifey, so you can bet that I put the Primemester Protocol to work for my own family too. I used the Primemester Protocol to get pregnant on the first try with each of my three babies as an “older” mom. I gave birth to my babies just before my 35th, 37th, and 40th birthdays, which means that, by the time I conceived my now two-year-old, I had, at most, 5% likelihood of conceiving on the first try. But I know that those calculations are based on averages in the general population, and

I had the science of primemester epigenetics on my side. So I planned to have all of my babies in March. Which is exactly what happened:

Baby #1 March 31, 2013

Baby #2 March 24, 2015

Baby #3 March 16, 2018 

The PRIME Method

At The Fertility & Pregnancy Institute, we use the system of secrets that I am about to teach you at each level of the fertility system—what we call, the Fertility Triangle. 

The system of secrets used in the Primemester Protocol is known as the PRIME Method:

Secret #1. Pregnant in No Time

Secret #2. Relationship & Intimacy

Secret #3. Inquiry of the Body & Brain

Secret #4. Mentally Fertile

Secret #5. Epigenetic Change

We all want to have our superbabies. At The Fertility & Pregnancy Institute (FPI), we define superbaby™ as the healthiest, happiest, brightest, most well-adjusted baby you can have given your and your partner’s genome and epigenome. Truthfully, though, we get that underlying the drive to have your superbabies is an even more primal desire: the desire to get pregnant quickly and easily, and to know that your body is working the way nature says it’s supposed to. 

So let’s dig a little deeper into Secret #1, Pregnant in No Time.

Pregnant in No Time

Getting pregnant in no time requires: (a) having access to the most ignited version of your fertility possible and (b) getting your knowledge of your fertile window down to a science.

Once you have your knowledge of your fertile window down to a science, there are two more steps. First, to confirm that you did, in fact, ovulate. Second, to ensure that the hormonal shifts that need to occur post-ovulation in order to allow a fertilized egg to implant and continue to grow are, in fact, occurring. Among these hormonal shifts is the rise in progesterone, which occurs following ovulation and peaks approximately seven days post-ovulation. When this rise in progesterone occurs and is sustained, it ensures that the luteal phase of your menstrual cycle is long enough to allow you to get pregnant and stay pregnant.

Historically, there were just two ways to confirm whether you ovulated. 

You could chart your temperature. This method has a significant margin of user error. As an example, if you wake up in the middle of the night to use the bathroom or you are traveling, your temperature—and, therefore, your charting—may be affected.

(As an aside, temperature charting is retrospective, not prospective. What I mean by this is that your temperature chart is better at telling you when ovulation has already occurred than it is at getting you the memo that ovulation is about to occur. This means that temperature charting isn’t the best tool for anticipating, and making the most of, your fertile window for superbaby-making.)

The other option was that you could go into your doctor’s office for a serum progesterone test.

(An interesting note here is that most doctors look for a progesterone level of 10 ng/mL or higher to indicate ovulation, but the scientific literature suggests that anything above 3 ng/mL indicates ovulation. Even with this difference of opinion, most obstetricians and fertility specialists agree that 10 ng/mL is the minimum level needed to be able to sustain a pregnancy if you are conceiving without medication or other medical intervention. Target levels are typically higher if you are using medications, such as Clomid, or are undergoing IVF.)

The good news is that now there is a third, even easier, option: Pregnanediol Glucuronide (PdG) at-home testing using urine. This is exactly what the Proov test strips make possible. Proov is a simple and easy way to confirm ovulation and to evaluate the health of your luteal phase. 

This is what we recommend to the Mamas-in-the-Making in the Primemester Protocol so that they can confirm ovulation and, if necessary, work on strengthening their luteal phase. You can do this, too, to help ensure that you get pregnant in no time.

Sending you all the baby dust, Mama!

Been trying for a baby with no luck, or planning to start trying soon? 

This checklist will get you on your way!

Get immediate access to the Ultimate 2-Minute Checklist of Scientifically Documented Strategies for Getting Pregnant, Reducing Miscarriage Risk, & Finally Having Your Superbaby.

Dr. Cleopatra is The Fertility Strategist and Executive Director of the Fertility & Pregnancy Institute. The mission of the Fertility & Pregnancy Institute is to see what others can’t using the best of love, science, and commitment to help ensure that your fertility keeps up with your high-achieving life so that you get to have as many superbabies as your heart desires.

Dr. Cleopatra is a scientist and university professor who pioneered the field of fertility biohacking and creating superbabies. To date, Dr. Cleopatra has scientifically studied tens of thousands of women and families and has helped women in their 20s, 30s, and 40s in 18 countries on 6 continents have their superbabies. She has received nearly $3 million in grant funding from the National Institutes of Health, the National Science Foundation, and private foundations, including the Robert Wood Johnson Foundation. Dr. Cleopatra has been cited in 1,000 scientific studies in the past 5 years alone. Dr. Cleopatra is the author of a forthcoming book on the primemester. Dr. Cleopatra teaches women to use the primemester™—the magical and powerful window of opportunity before pregnancy when we literally have the power to change the quality and expression of the genes that we pass down to our babies and grandbabies—to create their superbabies. Using the science-driven, big-hearted Primemester Protocol developed and refined by Dr. Cleopatra over the past 24 years, in combination with the cutting-edge technology of Fertility Epigenetic Tailoring, The Fertility & Pregnancy Institute helps women reverse reproductive aging; get pregnant quickly and easily; reduce miscarriage risk; and finally have the superbaby™ they’ve been dreaming of for as long as they can remember.

Have questions? Email us!