Now FDA Cleared! - 10% OFF YOUR FIRST ORDER! - Code: PROOVIT

Test, don't guess!

Let Proov Help your Patients at Home
Proov is the first and only FDA-Cleared Progesterone Test System to confirm ovulation at home - allowing you to provide virtual guidance and support without the need for a lab visit.

Empower more informed virtual treatment with FDA-cleared Proov test.


How Proov Works

Tracks PdG

Pregnanediol Glucuronide
(PdG) is the urine metabolite of progesterone

Multiple Days of Testing

Proov measures pregnanediol glucuronide (PdG) in first morning urine 7-10 days past ovulation

Better Than Blood

Testing PdG over multiple days provides more complete information than a one-time CD21 blood draw… Proov strips turn positive at 5 ug/ml of PdG in urine, which correlates to ~10 - ng/ml in serum

Digital Interface

Proov testing is done at home and results are communicated via the free Proov app or photos

Clinical Uses of Proov

Proov is most effective when used 7-10 dpo. Studies show PdG levels are high during this testing window in proven fertile women and act to enable proper implantation.

One Proov 7-Strip Kit Can:

Confirm ovulation

Diagnose luteal phase defect

Diagnose cause of recurrent miscarriage

Proov Works for Women With:

Polycystic Ovarian Syndrome (PCOS)


History of first trimester misscarriage

maternal age

Low Ovarian

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Device Validation Studies

1 Alliende 2018

• Proov has been clinically validated in 2 independent studies (Leiva 2019, Bouchard 2019).

• A laboratory study has shown this test to be over 99% accurate in detecting PdG in urine. The sensitivity of Proov is 5 ug/ml PdG.

• The lateral flow test strips are stable at 4-30° (39-86F) for 24 months based on the accelerated stability study at 42°.

• Devices showed no interference to common urine compounds such as: LH, HCG, Estone-3-Glucuronide, Acetaminophen, Ascorbic Acid, Caffeine, Glucose, Ampicillin, Ketone, Acetylsalicylic Acid, Atropine, Gentisic Acid, Hemoglobin, Tetracycline, Nitrites, Phenothiazine, Ethanol, and Albumin.

• Specific gravity or urine and urine pH don't affect device accuracy.

• Proov was compared to laboratory PdG EIA tests and shown only to be positive when PdG was >5ug/ml.

• A lay user study was conducted in 101 women and results demonstrate 99% of women can correctly read Proov results and 92% of women said device instructions and testing were easy or very easy.